To test a key prediction derived from simulated cortico-striatal circuit dynamics, we analysed task-related choice selections in participants characterised by different forms of compulsive behaviours. We used two three-option tasks with reversal learning and a modified Bayesian model that dynamically changes the pace of belief updating as a function of prior beliefs. We analysed choice behavior in tobacco product users, binge-eaters and patients with severe OCD to reveal: 1) a transdiagnostic decrease in the pace of belief updating (in comparison with matching healthy controls); and 2) diagnostic-specific alteration in the trial-by-trial dynamics of belief updating.


Prof. Vincenzo Fiore

Assistant Professor Center for Computational Psychiatry. Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.


Vincenzo Fiore – Dynamics of belief updating in compulsive behaviors

Leave a Reply